Description

3-(4-Amino-Piperidin-1-Yl)-1-(6-Chloro-Pyridin-3-Yl)-Propan-1-One is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents. It is essential for pharmaceutical R&D departments, process chemists, and manufacturers requiring reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric disorders.
• Active Pharmaceutical Ingredient (API) Synthesis: Used as a core building block for constructing complex molecular architectures in final API manufacturing.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP-compliant production of clinical trial materials and commercial drugs.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical laboratories.
• Chemical Biology Probes: Can be employed in the development of chemical probes for studying biological pathways and target validation.

Basic Information

Item	Details
Product Name	3-(4-Amino-Piperidin-1-Yl)-1-(6-Chloro-Pyridin-3-Yl)-Propan-1-One
CAS No.	886363-81-1
Molecular Formula	C13H18ClN3O
Molecular Weight	267.76 g/mol
Synonyms	1-(6-Chloro-3-pyridinyl)-3-(4-amino-1-piperidinyl)-1-propanone; 3-(4-Aminopiperidin-1-yl)-1-(6-chloropyridin-3-yl)propan-1-one; 886363-81-1; 1-Propanone, 3-(4-amino-1-piperidinyl)-1-(6-chloro-3-pyridinyl)-; 3-(4-Amino-1-piperidinyl)-1-(6-chloro-3-pyridinyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 3-(4-Amino-Piperidin-1-Yl)-1-(6-Chloro-Pyridin-3-Yl)-Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high standards, including cGMP manufacturing for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.