Description

6-Acetylamino-2-Spiro(n-Boc-Piperidine-4-Yl)-Benzopyran is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic benzopyran structure. This compound is critical for medicinal chemistry research and development, serving as a key building block for synthesizing novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Protease Inhibitor Synthesis: Potential building block for the development of protease inhibitors due to its structural motifs.
• Kinase Inhibitor Development: Employed in the synthesis of compounds targeting various kinase enzymes.
• Chemical Biology Probes: Serves as a starting material for creating molecular probes to study biological pathways.
• Academic & Contract Research: Essential for academic institutions and CROs (Contract Research Organizations) engaged in novel heterocyclic chemistry.

Basic Information

Product Name	6-Acetylamino-2-Spiro(n-Boc-Piperidine-4-Yl)-Benzopyran
CAS No.	886363-78-6
Molecular Formula	C21H28N2O4
Molecular Weight	372.46 g/mol
Synonyms	6-Acetamido-2-spiro(N-Boc-piperidin-4-yl)-4H-1-benzopyran; 2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)-6-acetamido-2H-chromene; 6-Acetylamino-2-spiro(1-N-Boc-piperidine-4-yl)-benzopyran; 6-Acetamido-2-(1-N-Boc-piperidin-4-yl)-2H-chromene; tert-Butyl 4-(6-acetamido-2H-chromen-2-yl)piperidine-1-carboxylate; 6-Acetylamino-2-spiro(N-Boc-4-piperidyl)-benzopyran; 6-Acetamido-2-(1-(tert-butoxycarbonyl)piperidin-4-yl)-2H-1-benzopyran
EINECS	Contact for details

Quality Control

Our 6-Acetylamino-2-Spiro(n-Boc-Piperidine-4-Yl)-Benzopyran is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting cGMP-compliant development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.