Description

2-Hydroxy-2-Pyridin-3-Yl-Cyclohexanone is a specialized organic compound featuring a cyclohexanone core substituted with a pyridine ring, making it a valuable chiral building block and synthetic intermediate. Its unique bifunctional structure, containing both a ketone and a hydroxyl group adjacent to a heterocyclic nitrogen, is critical for constructing complex molecules with specific stereochemistry and biological activity. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Asymmetric Catalysis: Serves as a precursor or ligand in catalytic systems for enantioselective synthesis due to its potential chiral centers.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Chemical Research: A versatile building block for synthesizing complex natural product analogs and other fine chemicals.
• Material Science Precursor: Investigated for the synthesis of specialized ligands used in metal-organic frameworks (MOFs) or functional materials.

Basic Information

Product Name	2-Hydroxy-2-Pyridin-3-Yl-Cyclohexanone
CAS No.	886362-93-2
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	2-(3-Pyridinyl)-2-hydroxycyclohexanone; 2-Hydroxy-2-(pyridin-3-yl)cyclohexan-1-one; 3-Pyridyl-2-hydroxycyclohexanone; 2-(3-Pyridyl)-2-hydroxycyclohexanone; 2-Hydroxy-2-(3-pyridyl)cyclohexanone; Cyclohexanone, 2-hydroxy-2-(3-pyridinyl)-; 886362-93-2
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-2-Pyridin-3-Yl-Cyclohexanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical specifications. Our quality commitment supports cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.