Description

3-Amino-3-(4'-Cbz)Piperidine-Propionic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology industries engaged in the development of novel therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, especially for neurological and psychiatric disorders.
• API Development: Used as a core structural component in the research and production of potential new chemical entities (NCEs).
• Peptidomimetics: Serves as a constrained amino acid analog for the design and synthesis of peptide-like molecules with enhanced metabolic stability.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for target molecules under Good Manufacturing Practice (GMP) conditions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-Amino-3-(4'-Cbz)Piperidine-Propionic Acid Ethyl Ester
CAS No.	886362-29-4
Molecular Formula	C18H26N2O4
Molecular Weight	334.41 g/mol
Synonyms	Ethyl 3-Amino-3-(4-[(benzyloxy)carbonyl]piperidin-1-yl)propanoate; 1-[(Benzyloxy)carbonyl]-3-(2-ethoxy-2-oxoethyl)-3-aminopiperidine; 3-Amino-3-(1-Cbz-piperidin-4-yl)propionic acid ethyl ester; 3-(1-[(Benzyloxy)carbonyl]piperidin-4-yl)-3-aminopropanoic acid ethyl ester; 886362-29-4; Cbz-protected 3-aminopiperidine propionate ester
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(4'-Cbz)Piperidine-Propionic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring material for GLP (Good Laboratory Practice) and cGMP (current Good Manufacturing Practice) environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.