Description

2-Chloro-4-(4-Fluorophenyl)Nicotinonitrile is a high-value, multi-functional chemical building block featuring a nicotinonitrile core substituted with chloro and fluorophenyl groups. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other biologically active heterocyclic compounds.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its fluorinated aromatic system.
• Material Science: Serves as a building block for organic electronic materials and liquid crystals due to its conjugated structure.
• Chemical Synthesis: Utilized in cross-coupling reactions and cyano-group transformations for creating diverse chemical libraries.
• Academic & Contract Research: Employed in universities and CROs for methodological studies and novel compound discovery.

Basic Information

Product Name	2-Chloro-4-(4-Fluorophenyl)Nicotinonitrile
CAS No.	886362-05-6
Molecular Formula	C12H6ClFN2
Molecular Weight	232.64 g/mol
Synonyms	2-Chloro-4-(4-fluorophenyl)nicotinonitrile; 2-Chloro-4-(p-fluorophenyl)-3-cyanopyridine; 3-Cyano-2-chloro-4-(4-fluorophenyl)pyridine; 4-(4-Fluorophenyl)-2-chloronicotinonitrile; 886362-05-6; 2-Chloro-4-(4-fluorophenyl)-3-pyridinecarbonitrile; Nicotinonitrile, 2-chloro-4-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-(4-Fluorophenyl)Nicotinonitrile is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.