Description

2-(4-Fluorophenyl)-5-Nitropyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct fluorinated aromatic and nitropyridine structure. This compound is critical for research and development in medicinal chemistry, where it serves as a versatile building block for creating novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, agrochemical manufacturers, and academic institutions focused on heterocyclic and fluorinated compound synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the biological activity of the nitropyridine moiety.
• Material Science: Acts as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Serves as a versatile scaffold for further functionalization, including reduction, cross-coupling, and nucleophilic substitution reactions.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-(4-Fluorophenyl)-5-Nitropyridine
CAS No.	886361-78-0
Molecular Formula	C11H7FN2O2
Molecular Weight	218.19 g/mol
Synonyms	5-Nitro-2-(4-fluorophenyl)pyridine; 2-(4-Fluorophenyl)-5-nitropyridine; 4-Fluoro-5-nitropyridine-2-phenyl; (4-Fluorophenyl)-5-nitropyridine; 886361-78-0; 2-(p-Fluorophenyl)-5-nitropyridine
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)-5-Nitropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound should be kept under inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.