Description

1-Benzyl-5-Bromo-1,6-Dihydro-6-Oxonicotinic Acid, 1-Benzyl-3-Bromo-5-Carboxypyridin-2(1H)-One is a high-value brominated pyridone derivative, serving as a critical synthetic intermediate for advanced pharmaceutical and agrochemical research. Its unique structure, featuring both a carboxylic acid and a bromine substituent, makes it a versatile building block for constructing complex molecules through cross-coupling and functional group transformations. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridone core for bioactivity.
• Chemical Synthesis: Serves as a versatile precursor for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to introduce complex aryl and heteroaryl groups.
• Material Science: Potential monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Academic & Contract Research: Essential reagent for university laboratories and CROs (Contract Research Organizations) conducting exploratory organic synthesis and method development.

Basic Information

Product Name	1-Benzyl-5-Bromo-1,6-Dihydro-6-Oxonicotinic Acid, 1-Benzyl-3-Bromo-5-Carboxypyridin-2(1H)-One
CAS No.	886361-76-8
Molecular Formula	C14H10BrNO3
Molecular Weight	320.14 g/mol
Synonyms	1-Benzyl-3-bromo-5-carboxypyridin-2(1H)-one; 1-Benzyl-5-bromo-1,6-dihydro-6-oxonicotinic acid; 5-Bromo-1-benzyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid; 3-Bromo-1-benzyl-2-oxo-1,2-dihydro-5-pyridinecarboxylic acid; 1-Benzyl-5-bromo-6-oxo-1,6-dihydropyridine-3-carboxylic acid; BBOPC; 886361-76-8
EINECS	Contact for details

Quality Control

Our 1-Benzyl-5-Bromo-1,6-Dihydro-6-Oxonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.