Description

4-[5-(Chloromethyl)-2-Pyridinyl]Benzenecarbaldehyde is a versatile and high-value aromatic aldehyde building block featuring both a reactive chloromethyl group and a formyl group on a bipyridyl-benzene scaffold. This bifunctional nature makes it a critical intermediate for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing novel active pharmaceutical ingredients (APIs), ligands, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Chelator Production: Serves as a starting material for creating complexing agents and catalysts used in metal-organic chemistry and industrial catalysis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: The chloromethyl and aldehyde groups provide handles for various palladium-catalyzed and nucleophilic substitution reactions.
• Bioconjugation and Probe Development: Useful for creating fluorescent probes or affinity labels for biochemical and diagnostic applications.

Basic Information

Product Name	4-[5-(Chloromethyl)-2-Pyridinyl]Benzenecarbaldehyde
CAS No.	886361-70-2
Molecular Formula	C13H10ClNO
Molecular Weight	231.68 g/mol
Synonyms	4-(5-(Chloromethyl)pyridin-2-yl)benzaldehyde; 2-(4-Formylphenyl)-5-(chloromethyl)pyridine; [5-(Chloromethyl)-2-pyridinyl]benzaldehyde; 5-(Chloromethyl)-2-(4-formylphenyl)pyridine; 4-(5-Chloromethyl-pyridin-2-yl)-benzaldehyde; 886361-70-2; 4-[5-(Chloromethyl)-2-pyridyl]benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-[5-(Chloromethyl)-2-Pyridinyl]Benzenecarbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.