Description

2-Chloro-4,6-Dimethyl-3-(Methylsulfonyl)Pyridine is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique sulfonyl and chloro substituents make it a versatile intermediate for constructing complex molecular architectures with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functional organic materials, such as liquid crystals, organic semiconductors, and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical market.

Basic Information

Product Name	2-Chloro-4,6-Dimethyl-3-(Methylsulfonyl)Pyridine
CAS No.	886361-59-7
Molecular Formula	C8H10ClNO2S
Molecular Weight	219.69 g/mol
Synonyms	3-(Methylsulfonyl)-2-chloro-4,6-dimethylpyridine; 2-Chloro-4,6-dimethyl-3-methylsulfonylpyridine; 2-Chloro-3-(methylsulfonyl)-4,6-dimethylpyridine; 4,6-Dimethyl-2-chloro-3-(methylsulfonyl)pyridine; Pyridine, 2-chloro-4,6-dimethyl-3-(methylsulfonyl)-; 886361-59-7
EINECS	Contact for details

Quality Control

Our 2-Chloro-4,6-Dimethyl-3-(Methylsulfonyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.