Description

1-[2-Amino-5-(4-Methylpiperidin-1-Yl)Phenyl]-1-Ethanone is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining an aminophenyl ketone with a 4-methylpiperidine moiety. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily utilized by research institutions, custom synthesis organizations, and pharmaceutical manufacturers engaged in drug discovery and process development. The material is supplied under stringent quality control to ensure batch-to-batch consistency for reliable research and scale-up.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule production.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in API manufacturing.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.

Basic Information

Item	Details
Product Name	1-[2-Amino-5-(4-Methylpiperidin-1-Yl)Phenyl]-1-Ethanone
CAS No.	886361-39-3
Molecular Formula	C14H20N2O
Molecular Weight	232.32 g/mol
Synonyms	1-(2-Amino-5-(4-methylpiperidin-1-yl)phenyl)ethanone; 2'-Amino-5'-(4-methyl-1-piperidinyl)acetophenone; Ethanone, 1-[2-amino-5-(4-methyl-1-piperidinyl)phenyl]-; 886361-39-3; 4-Methyl-1-[3-acetyl-4-aminophenyl]piperidine
EINECS	Contact for details

Quality Control

Our 1-[2-Amino-5-(4-Methylpiperidin-1-Yl)Phenyl]-1-Ethanone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to confirm identity and purity. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with customer specifications. Our quality protocols are designed to meet the rigorous standards required for pharmaceutical R&D and pre-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture uptake and oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.