Description

2-(3-Aminophenyl)-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional aromatic amine building block characterized by its unique trifluoromethylpyridine and aniline moieties. This compound is critical for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structural features impart desirable properties like metabolic stability and enhanced lipophilicity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity.
• Ligand & Catalyst Development: Serves as a versatile building block for creating chelating ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials.
• Chemical Biology Probes: Useful for constructing fluorescent tags or affinity probes due to its amine handle for conjugation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, complex aromatic amines.

Basic Information

Product Name	2-(3-Aminophenyl)-5-(Trifluoromethyl)Pyridine
CAS No.	886361-00-8
Molecular Formula	C12H9F3N2
Molecular Weight	238.21 g/mol
Synonyms	3-(5-(Trifluoromethyl)pyridin-2-yl)aniline; 2-(3-Aminophenyl)-5-(trifluoromethyl)pyridine; [3-(5-Trifluoromethyl-2-pyridyl)phenyl]amine; 5-(Trifluoromethyl)-2-(3-aminophenyl)pyridine; 3-(5-Trifluoromethylpyridin-2-yl)benzenamine; 2-(3-Aminophenyl)-5-trifluoromethylpyridine; 3-(5-Trifluoromethyl-2-pyridinyl)aniline; 3-Amino-5'-(trifluoromethyl)-2,3'-bipyridine
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Aminophenyl)-5-(Trifluoromethyl)Pyridine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.