Description

3-Pyridinepropanoic Acid, A-Amino-6-(Trifluoromethyl)-, Methyl Ester, (As)- is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and trifluoromethyl-substituted pyridine core. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, agrochemicals, and other fine chemical products where precise chemical architecture is paramount.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and protein interactions within biological systems.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with unique electronic or surface properties.

Basic Information

Product Name	3-Pyridinepropanoic Acid, A-Amino-6-(Trifluoromethyl)-, Methyl Ester, (As)-
CAS No.	886215-55-0
Molecular Formula	C10H11F3N2O2
Molecular Weight	248.20 g/mol
Synonyms	(αS)-α-Amino-6-(trifluoromethyl)-3-pyridinepropanoic acid methyl ester; Methyl (S)-2-amino-3-(6-(trifluoromethyl)pyridin-3-yl)propanoate; (S)-Methyl 2-amino-3-(6-(trifluoromethyl)pyridin-3-yl)propanoate; 886215-55-0; (As)-A-Amino-6-(Trifluoromethyl)-3-pyridinepropanoic Acid Methyl Ester; (S)-2-Amino-3-(6-(trifluoromethyl)-3-pyridyl)propionic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Pyridinepropanoic Acid, A-Amino-6-(Trifluoromethyl)-, Methyl Ester, (As)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.