Description

3-Hydroxymethyl-5-(4-Trifluoromethylphenyl)Pyridine is a high-value trifluoromethylated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure combines a hydroxymethyl functional group with a lipophilic trifluoromethylphenyl moiety, making it an essential intermediate for creating compounds with enhanced bioavailability and metabolic stability. This product is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used to develop novel pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Fluorinated Building Block: Essential for introducing the trifluoromethyl group into more complex molecular architectures in medicinal and synthetic chemistry.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and target engagement.

Basic Information

Product Name	3-Hydroxymethyl-5-(4-Trifluoromethylphenyl)Pyridine
CAS No.	885959-16-0
Molecular Formula	C13H10F3NO
Molecular Weight	253.22 g/mol
Synonyms	[5-(4-Trifluoromethylphenyl)pyridin-3-yl]methanol; 3-(Hydroxymethyl)-5-[4-(trifluoromethyl)phenyl]pyridine; 5-(4-Trifluoromethylphenyl)pyridine-3-methanol; 3-Pyridinemethanol, 5-[4-(trifluoromethyl)phenyl]-; α-(5-(4-(Trifluoromethyl)phenyl)pyridin-3-yl)methanol
EINECS	Contact for details

Quality Control

Our 3-Hydroxymethyl-5-(4-Trifluoromethylphenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.