Description

2-Boc-Aminopiperidine is a protected piperidine derivative of significant importance in synthetic organic chemistry. This compound serves as a versatile and critical building block for the construction of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those containing piperidine scaffolds, such as kinase inhibitors, receptor antagonists, and central nervous system (CNS) active compounds.
• Peptidomimetic Chemistry: Used to introduce protected amine functionalities into peptide analogs and peptidomimetics to modulate biological activity and pharmacokinetic properties.
• Ligand and Catalyst Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis and as a component in organocatalysts.
• Agrochemical Development: Acts as a building block for creating novel herbicides, fungicides, and insecticides that require specific amine-protected intermediates.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, protected heterocyclic amines.
• Academic and R&D: Utilized in university and institutional research laboratories for methodological development and exploratory synthesis of new chemical entities.

Basic Information

Product Name	2-Boc-Aminopiperidine
CAS No.	885954-12-1
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	1-Boc-2-Aminopiperidine; tert-Butyl 2-Aminopiperidine-1-carboxylate; 2-Amino-1-N-Boc-piperidine; 1-(tert-Butoxycarbonyl)-2-aminopiperidine; 2-(Boc-Amino)piperidine; N-Boc-2-piperidinamine; Piperidine, 2-amino-1-[(1,1-dimethylethoxy)carbonyl]-; 2-Amino-N-Boc-piperidine
EINECS	Contact for details

Quality Control

Our 2-Boc-Aminopiperidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, assay, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.