Description

6-(Bromomethyl)Picolinic Acid is a versatile brominated picolinic acid derivative that serves as a critical building block in advanced organic synthesis. Its reactive bromomethyl group adjacent to the carboxylic acid functionality makes it a valuable bifunctional intermediate for constructing complex molecular architectures. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing pyridine and heterocyclic motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the picolinate structure is often bioactive.
• Ligand and Chelator Preparation: Serves as a starting material for synthesizing specialized ligands used in catalysis, metal complexation, and medicinal chemistry.
• Linker in Bioconjugation: The reactive bromomethyl group enables its use as a linker for attaching payloads in antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Material Science Research: Employed in the development of organic semiconductors, metal-organic frameworks (MOFs), and other functional polymers.
• Chemical Biology Probes: Useful for creating chemical probes and inhibitors to study enzyme function and biological pathways.

Basic Information

Product Name	6-(Bromomethyl)Picolinic Acid
CAS No.	885951-67-7
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	2-Bromomethyl-6-pyridinecarboxylic Acid; 6-(Bromomethyl)pyridine-2-carboxylic Acid; 2-Picolinic Acid, 6-(bromomethyl)-; Picolinic Acid, 6-(bromomethyl)-; 6-Bromomethylpicolinic Acid; (6-Bromomethyl)pyridine-2-carboxylic Acid; 2-Carboxy-6-bromomethylpyridine
EINECS	Contact for details

Quality Control

Our 6-(Bromomethyl)Picolinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.