Description

Methyl 5-Chloro-6-(Phenylsulfanyl)Nicotinate is a high-purity, advanced pharmaceutical intermediate characterized by its unique nicotinate core functionalized with chloro and phenylsulfanyl substituents. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals. The material is supplied under stringent quality control to ensure batch-to-batch consistency for critical synthetic applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and fungicides due to its bioactive heterocyclic structure.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization in organic and medicinal chemistry research.
• Material Science: Potential intermediate for creating specialized ligands or functional molecules in advanced material applications.

Basic Information

Product Name	Methyl 5-Chloro-6-(Phenylsulfanyl)Nicotinate
CAS No.	885951-48-4
Molecular Formula	C13H10ClNO2S
Molecular Weight	279.74 g/mol
Synonyms	5-Chloro-6-(phenylthio)nicotinic acid methyl ester; Methyl 5-chloro-6-(phenylthio)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-chloro-6-(phenylthio)-, methyl ester; 885951-48-4; Methyl 5-chloro-6-phenylsulfanylpyridine-3-carboxylate; 5-Chloro-6-(phenylsulfanyl)nicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Chloro-6-(Phenylsulfanyl)Nicotinate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and the absence of critical impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with customer specifications and relevant industry guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.