Description

Methyl 2-(3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl)Acetate is a high-value pyridine derivative ester, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it an essential building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, insecticides, and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel pyridine-based ligands for catalytic systems.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Methyl 2-(3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl)Acetate
CAS No.	885949-63-3
Molecular Formula	C9H7ClF3NO2
Molecular Weight	253.60 g/mol
Synonyms	Methyl (3-Chloro-5-(trifluoromethyl)pyridin-2-yl)acetate; 2-(3-Chloro-5-(trifluoromethyl)-2-pyridinyl)acetic acid methyl ester; Methyl 2-(3-chloro-5-(trifluoromethyl)-2-pyridyl)acetate; 885949-63-3; Acetic acid, 2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl)Acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous internal specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and impurity profiles is provided with every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This compound is sensitive to fluoride/strong alkali; ensure it is stored separately from such materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5% Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.