Description

1,4-Bis-(4-Methoxy-Benzyl)-7-Phenyl-6-Thioxo-1,4,7-Triaza-Spiro[4.4]Non-8-Ene-9-Carboxylic Acid Ethyl Ester is a sophisticated spirocyclic organic compound featuring a unique triaza-thioxo core structure. This high-value intermediate is critical for advanced research and development in medicinal chemistry, particularly in the synthesis of novel pharmacologically active molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or acting as enzyme inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel bioactive molecules.
• Heterocyclic Compound Synthesis: Serves as a precursor for constructing complex spirocyclic and fused ring systems with potential biological activity.
• Chemical Biology Probes: Can be utilized in the development of chemical probes for studying biological pathways and protein functions.
• Academic & Institutional R&D: Employed in university and research institute laboratories for exploratory synthetic chemistry and new methodology development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Item	Details
Product Name	1,4-Bis-(4-Methoxy-Benzyl)-7-Phenyl-6-Thioxo-1,4,7-Triaza-Spiro[4.4]Non-8-Ene-9-Carboxylic Acid Ethyl Ester
CAS No.	885722-40-7
Molecular Formula	C35H35N3O4S
Molecular Weight	593.74 g/mol
Synonyms	Ethyl 1,4-bis(4-methoxybenzyl)-7-phenyl-6-thioxo-1,4,7-triazaspiro[4.4]non-8-ene-9-carboxylate; 1,4,7-Triazaspiro[4.4]non-8-ene-9-carboxylic acid, 1,4-bis(4-methoxybenzyl)-7-phenyl-6-thioxo-, ethyl ester; 885722-40-7; Spirocyclic triaza-thioxo ester; 1,4-Bis-(4-Methoxy-Benzyl)-7-Phenyl-6-Thioxo-1,4,7-Triaza-Spiro[4.4]Non-8-Ene-9-Carboxylate Ethyl Ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for purity, identity, and related substances. Our quality management system supports development under cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.