Description

4-Piperidinamine, 1-[(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Methyl]- is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core fused with a benzodioxane moiety. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) due to its unique structural framework, which imparts specific biological activity and binding properties. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within the central nervous system (CNS) and cardiovascular drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting G-protein-coupled receptors (GPCRs).
• Neurological Research: Used in the development of potential therapeutics for conditions such as anxiety, depression, and neurodegenerative diseases.
• Cardiovascular Drug Development: Serves as a precursor for compounds being investigated for hypertension and arrhythmia.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or linker in the design of chemical probes for target identification and validation.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and cGMP manufacturing of clinical trial materials.
• Contract Research & Development (CRO/CMO): Essential raw material for organizations providing custom synthesis and process development services.

Basic Information

Product Name	4-Piperidinamine, 1-[(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Methyl]-
CAS No.	885721-61-9
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	1-[(2,3-Dihydro-1,4-benzodioxin-6-yl)methyl]piperidin-4-amine; 4-Amino-1-[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]piperidine; 1-(1,4-Benzodioxan-6-ylmethyl)-4-aminopiperidine; 6-[(4-Aminopiperidin-1-yl)methyl]-2,3-dihydro-1,4-benzodioxine; 885721-61-9; 4-Piperidinamine, 1-[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]- (9CI)
EINECS	Contact for details

Quality Control

Our 4-Piperidinamine, 1-[(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Methyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with the standards expected for pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.