Description

(3-Bromo-4-Fluorophenyl)Acetic Acid Methyl Ester is a high-purity fluorinated and brominated aromatic building block essential for advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex, biologically active molecules, offering distinct reactivity for selective functionalization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and CNS-active molecule libraries.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging the halogenated phenyl moiety for enhanced bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores in electronic and display material manufacturing.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: A valuable reagent in academic and industrial labs for exploring new synthetic methodologies and creating specialized compound libraries.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	(3-Bromo-4-Fluorophenyl)Acetic Acid Methyl Ester
CAS No.	885681-61-8
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	Methyl (3-bromo-4-fluorophenyl)acetate; 2-(3-Bromo-4-fluorophenyl)acetic acid methyl ester; Methyl 2-(3-bromo-4-fluorophenyl)acetate; (3-Bromo-4-fluorobenzene)acetic acid methyl ester; 3-Bromo-4-fluorophenylacetic acid methyl ester; Methyl (3-bromo-4-fluorobenzene)acetate; 885681-61-8
EINECS	Contact for details

Quality Control

Our (3-Bromo-4-Fluorophenyl)Acetic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.