Description

2-Fluoro-3-Methylisonicotinic Acid is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which introduces both fluorine and a carboxylic acid functional group onto the pyridine ring, enabling precise modifications in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials that require fluorinated aromatic components.
• Chemical Biology Probes: Utilized to create fluorinated analogs of natural products or biomarkers for metabolic and binding studies.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-3-Methylisonicotinic Acid
CAS No.	885589-17-3
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	2-Fluoro-3-methylpyridine-4-carboxylic acid; 3-Methyl-2-fluoroisonicotinic acid; 4-Pyridinecarboxylic acid, 2-fluoro-3-methyl-; 2-Fluoro-3-methyl-4-pyridinecarboxylic acid; 2-Fluoro-3-picolinic acid (ambiguous); 2-Fluoro-3-methylisonicotinate; 885589-17-3
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Methylisonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.