Description

5-Fluoro-2-Methyl-4-Pyridinecarboxylic Acid is a high-value fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular modifications to develop novel active compounds. It is primarily utilized in the pharmaceutical and agrochemical industries for the research and development of new active ingredients, where its unique substitution pattern offers strategic advantages in molecular design and optimization.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Useful for creating fluorinated analogs of bioactive molecules to study metabolic pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	5-Fluoro-2-Methyl-4-Pyridinecarboxylic Acid
CAS No.	885588-17-0
Molecular Formula	C8H6FNO2
Molecular Weight	167.14 g/mol
Synonyms	4-Pyridinecarboxylic acid, 5-fluoro-2-methyl-; 5-Fluoro-2-picolinic acid; 2-Methyl-5-fluoroisonicotinic acid; 5-Fluoro-2-methylisonicotinic acid; 5-Fluoro-2-methylpyridine-4-carboxylic acid; 2-Methyl-5-fluoropyridine-4-carboxylic acid; 885588-17-0; FC-2341 (Potential Research Code)
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methyl-4-Pyridinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.