Description

2-Bromo-5-Fluoroisonicotinic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its unique halogenated pyridine structure, which serves as a critical precursor for constructing complex molecules with tailored biological and physical properties. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated heterocycle for bioactivity.
• Ligand and Catalyst Development: Serves as a versatile precursor for creating specialized ligands used in transition metal catalysis and material science.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems and diagnostic applications.
• Material Science Research: Utilized as a monomer or building block for developing novel polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-5-Fluoroisonicotinic Acid
CAS No.	885588-12-5
Molecular Formula	C6H3BrFNO2
Molecular Weight	219.99 g/mol
Synonyms	5-Fluoro-2-bromoisonicotinic acid; 2-Bromo-5-fluoropyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 2-bromo-5-fluoro-; Isonicotinic acid, 2-bromo-5-fluoro-; 885588-12-5; 2-Br-5-F-4-PyCOOH
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluoroisonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is compatible with strong acids and organic solvents but should be kept separate from incompatible materials. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.