Description

1H-Indazole-6-Carboxylic Acid,3-Iodo-,Methyl Ester is a high-value iodinated indazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of targeted bioactive molecules. Pharmaceutical researchers and fine chemical manufacturers need it for applications in medicinal chemistry, including the synthesis of potential kinase inhibitors and other pharmacologically active compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Chemical Biology Probes: Serves as a precursor for labeled compounds used in biochemical assays and imaging studies.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce the iodinated indazole moiety into more complex molecules.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents with specific modes of action.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical reactions.

Basic Information

Product Name	1H-Indazole-6-Carboxylic Acid,3-Iodo-,Methyl Ester
CAS No.	885518-82-1
Molecular Formula	C9H7IN2O2
Molecular Weight	302.07 g/mol
Synonyms	Methyl 3-iodo-1H-indazole-6-carboxylate; 3-Iodo-1H-indazole-6-carboxylic acid methyl ester; 1H-Indazole-6-carboxylic acid, 3-iodo-, methyl ester; 885518-82-1; Methyl 3-iodoindazole-6-carboxylate; 3-Iodo-6-(methoxycarbonyl)-1H-indazole; 3-Iodo-1H-indazole-6-methyl carboxylate
EINECS	Contact for details

Quality Control

Our production of 1H-Indazole-6-Carboxylic Acid,3-Iodo-,Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released according to comprehensive in-house specifications, which typically include identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) detailing all relevant parameters are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent contamination and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.