Description

6-Chloro-1-Isopropyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its pyrazolopyridine core structure. This compound is essential for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) engaged in synthetic chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Organic Synthesis: Serves as a versatile precursor for further functionalization via reactions at the aldehyde and chloro substituents.
• Agrochemical Development: Potential intermediate in the research of novel crop protection agents and pesticides.
• Material Science: Investigated as a precursor for specialty chemicals and functional materials with specific electronic properties.

Basic Information

Product Name	6-Chloro-1-Isopropyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbaldehyde
CAS No.	885461-63-2
Molecular Formula	C10H10ClN3O
Molecular Weight	223.66 g/mol
Synonyms	6-Chloro-1-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde; 1H-Pyrazolo[3,4-b]pyridine-5-carboxaldehyde, 6-chloro-1-(1-methylethyl)-; 6-Chloro-1-isopropyl-1H-pyrazolo[3,4-b]pyridine-5-carboxaldehyde; 6-Chloro-1-isopropyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde; 885461-63-2
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-1-Isopropyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carbaldehyde adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be sealed immediately after use to minimize exposure to air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.