Description

4-Bromo-6-[(tert-Butoxycarbonyl)Amino]Pyridine-2-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex molecules, particularly in the creation of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its functionalized pyridine core.
• Organic Synthesis Building Block: Serves as a versatile reagent for constructing complex heterocyclic compounds in medicinal chemistry.
• Research & Development (R&D): Essential for academic and industrial R&D labs focused on developing new chemical entities and exploring structure-activity relationships.
• Peptide Mimetics: The Boc-protected amino group makes it valuable for creating peptide-like structures and bioisosteres in drug design.

Basic Information

Product Name	4-Bromo-6-[(tert-Butoxycarbonyl)Amino]Pyridine-2-Carboxylic Acid Methyl Ester
CAS No.	885326-87-4
Molecular Formula	C12H15BrN2O4
Molecular Weight	331.17 g/mol
Synonyms	Methyl 4-Bromo-6-[(tert-butoxycarbonyl)amino]pyridine-2-carboxylate; 4-Bromo-6-(Boc-amino)picolinic Acid Methyl Ester; 6-(Boc-amino)-4-bromopicolinic Acid Methyl Ester; 2-Pyridinecarboxylic acid, 4-bromo-6-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester; Methyl 4-bromo-6-(N-Boc-amino)picolinate; Boc-6-Amino-4-bromopicolinic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-[(tert-Butoxycarbonyl)Amino]Pyridine-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.