Description

(R)-4-tert-Butyl 3-Methyl Morpholine-3,4-Dicarboxylate CAS NO 885321-46-0 is a high-purity chiral morpholine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a stereochemically defined building block for constructing complex molecules, enabling precise control over the final product's three-dimensional structure. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals where chirality is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of novel drug candidates, especially for central nervous system (CNS) and antiviral targets.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
• Catalyst & Ligand Development: Serves as a precursor for the synthesis of novel chiral ligands and organocatalysts used in asymmetric catalysis.
• Academic & Industrial R&D: A valuable tool for method development in stereoselective synthesis and for exploring new chemical spaces in medicinal chemistry.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	(R)-4-tert-Butyl 3-Methyl Morpholine-3,4-Dicarboxylate
CAS No.	885321-46-0
Molecular Formula	C12H21NO5
Molecular Weight	259.30 g/mol
Synonyms	(3R)-4-(tert-Butoxycarbonyl)-3-methylmorpholine-3-carboxylic acid; (R)-4-Boc-3-methylmorpholine-3-carboxylic acid; (R)-1-Boc-3-methylmorpholine-3-carboxylic acid; (R)-3-Methyl-4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid; 4-tert-Butyl (3R)-3-methylmorpholine-3,4-dicarboxylate; (R)-4-tert-Butyl 3-methylmorpholine-3,4-dicarboxylate; 885321-46-0; (R)-Boc-methyl morpholine carboxylate
EINECS	Contact for details

Quality Control

Our (R)-4-tert-Butyl 3-Methyl Morpholine-3,4-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is stable under inert atmosphere. Keep away from strong acids and organic solvents as indicated by its chemical properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.