Description

6-(2-Amino-Phenyl)-Nicotinonitrile is a high-purity, specialized organic intermediate featuring a unique biaryl structure with both amino and nitrile functional groups. This compound is critical for the synthesis of complex heterocyclic systems and advanced pharmaceutical scaffolds, offering precise reactivity for targeted molecular construction. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors, receptor antagonists, and other novel therapeutic agents targeting central nervous system and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its structural motif for bioactivity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Chemical Biology Probes: Utilized as a core structure for designing fluorescent probes and activity-based protein profiling (ABPP) agents.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, multi-step organic transformations.

Basic Information

Product Name	6-(2-Amino-Phenyl)-Nicotinonitrile
CAS No.	885277-25-8
Molecular Formula	C₁₂H₉N₃
Molecular Weight	195.22 g/mol
Synonyms	2-Amino-6-(2-aminophenyl)nicotinonitrile; 6-(2-Aminophenyl)pyridine-3-carbonitrile; 3-Cyano-6-(2-aminophenyl)pyridine; 2'-Amino-[2,3']bipyridinyl-5'-carbonitrile; (2-Aminophenyl)(5-cyano-2-pyridinyl)amine; 6-(2-Aminophenyl)nicotinonitrile; 885277-25-8; 2-Amino-6-(2-aminophenyl)-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 6-(2-Amino-Phenyl)-Nicotinonitrile is manufactured and tested under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Our standard quality commitment includes verification of identity, purity, and impurity profiles using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.