Description

2-Azepan-1-Yl-Isonicotinic Acid Hydrochloride is a high-purity chemical building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its functionalized heterocyclic structure, which serves as a key precursor for the development of novel pharmacologically active compounds. This product is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, drug discovery, and the synthesis of complex molecules for biological screening.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new chemical entities with improved efficacy and safety profiles.
• Chemical Synthesis: Serves as a versatile precursor for constructing complex heterocyclic frameworks and functionalized azepane derivatives.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or molecular probes for biochemical and pharmacological research applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	2-Azepan-1-Yl-Isonicotinic Acid Hydrochloride
CAS No.	885277-05-4
Molecular Formula	C13H19N3O2 • HCl
Molecular Weight	285.77 g/mol (free base: 249.31 g/mol)
Synonyms	2-(Azepan-1-yl)isonicotinic acid hydrochloride; 2-(1-Azepanyl)isonicotinic Acid Hydrochloride; 2-(Hexamethyleneimino)isonicotinic Acid Hydrochloride; 4-Pyridinecarboxylic acid, 2-(hexahydro-1H-azepin-1-yl)-, hydrochloride; Isonicotinic acid, 2-(azepan-1-yl)-, hydrochloride; 885277-05-4; 2-Azepan-1-yl-isonicotinic acid HCl
EINECS	Contact for details

Quality Control

Our 2-Azepan-1-Yl-Isonicotinic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.