Description

3-Iodo-Imidazo[1,2-A]Pyridine-8-Carboxylic Acid Methyl Ester is a high-value, halogenated heterocyclic building block crucial for advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its reactive iodine and ester functional groups.
• Agrochemical Development: Serves as a precursor in the creation of new pesticides and herbicides with enhanced efficacy.
• Material Science: Potential monomer or precursor for the synthesis of specialty polymers and organic electronic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Chemical Biology Probes: Used in the development of molecular probes and tags for studying biological systems.

Basic Information

Product Name	3-Iodo-Imidazo[1,2-A]Pyridine-8-Carboxylic Acid Methyl Ester
CAS No.	885276-95-9
Molecular Formula	C9H7IN2O2
Molecular Weight	302.07 g/mol
Synonyms	Methyl 3-iodoimidazo[1,2-a]pyridine-8-carboxylate; 3-Iodoimidazo[1,2-a]pyridine-8-carboxylic acid methyl ester; Imidazo[1,2-a]pyridine-8-carboxylic acid, 3-iodo-, methyl ester; 885276-95-9; 3-Iodo-8-methoxycarbonylimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 3-Iodo-Imidazo[1,2-A]Pyridine-8-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.