Description

8-Benzyloxy-3-Iodo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the synthesis of novel bioactive molecules, particularly in the development of kinase inhibitors and other targeted therapies. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel imidazopyridine-based drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile reactive sites.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the creation of potential kinase inhibitors for oncology and inflammatory disorders.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of complex molecules under cGMP or research-grade conditions.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and new methodology development.

Basic Information

Product Name	8-Benzyloxy-3-Iodo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester
CAS No.	885276-85-7
Molecular Formula	C17H15IN2O3
Molecular Weight	422.22 g/mol
Synonyms	Ethyl 8-(benzyloxy)-3-iodoimidazo[1,2-a]pyridine-2-carboxylate; 8-Benzyloxy-3-iodoimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester; Imidazo[1,2-a]pyridine-2-carboxylic acid, 8-(phenylmethoxy)-3-iodo-, ethyl ester; 885276-85-7; Ethyl 3-iodo-8-(phenylmethoxy)imidazo[1,2-a]pyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 8-Benzyloxy-3-Iodo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports both research and development-scale projects, with the capability to meet cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.