Description

2-Chloromethyl-Imidazo[1,2-A]Pyridine-8-Carboxylic Acid Methyl Ester is a high-value heterocyclic building block and key synthetic intermediate in advanced organic chemistry. This compound matters for its crucial role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical R&D and fine chemical synthesis laboratories need this precise intermediate to enable efficient and scalable routes to target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its fused heterocyclic structure for biological activity.
• Material Science: Serves as a building block for creating specialized organic ligands and functional molecules with potential electronic or photonic properties.
• Academic & Contract Research: Essential for medicinal chemistry programs and process development in academic institutions and CROs/CDMOs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	2-Chloromethyl-Imidazo[1,2-A]Pyridine-8-Carboxylic Acid Methyl Ester
CAS No.	885276-65-3
Molecular Formula	C11H9ClN2O2
Molecular Weight	236.65 g/mol
Synonyms	Methyl 2-(chloromethyl)imidazo[1,2-a]pyridine-8-carboxylate; 8-Methoxycarbonyl-2-chloromethylimidazo[1,2-a]pyridine; 2-Chloromethylimidazo[1,2-a]pyridine-8-carboxylic acid methyl ester; Imidazo[1,2-a]pyridine-8-carboxylic acid, 2-(chloromethyl)-, methyl ester; CAS 885276-65-3
EINECS	Contact for details

Quality Control

Our production of 2-Chloromethyl-Imidazo[1,2-A]Pyridine-8-Carboxylic Acid Methyl Ester adheres to stringent quality protocols suitable for research and development applications. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical properties are provided and available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.