Description

(3-Boc-Amino-Pyrrolidin-1-Yl)-Pyridin-4-Yl-Acetic Acid CAS NO 885276-64-2 is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold that combines a Boc-protected pyrrolidine with a pyridyl-acetic acid moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of small molecule drugs, particularly those targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Protease Inhibitor Synthesis: The pyrrolidine-pyridine core structure is valuable for constructing molecules that target various protease enzymes.
• Ligand Development: Serves as a precursor for creating novel ligands in catalyst systems or for biological target modulation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: Used in university and institutional labs for exploratory organic synthesis and biochemical studies.

Basic Information

Item	Details
Product Name	(3-Boc-Amino-Pyrrolidin-1-Yl)-Pyridin-4-Yl-Acetic Acid
CAS No.	885276-64-2
Molecular Formula	C16H23N3O4
Molecular Weight	321.37 g/mol
Synonyms	1-(4-Carboxymethylpyridin-2-yl)-3-[(tert-butoxycarbonyl)amino]pyrrolidine; 2-{4-[3-[(tert-Butoxycarbonyl)amino]-1-pyrrolidinyl]pyridin-2-yl}acetic Acid; (3-{[(tert-Butoxycarbonyl)amino]}pyrrolidin-1-yl)(4-pyridyl)acetic Acid; 2-(4-((3-((tert-Butoxycarbonyl)amino)pyrrolidin-1-yl)methyl)pyridin-2-yl)acetic Acid; Boc-3-Amino-pyrrolidin-1-yl-pyridin-4-yl-acetic Acid; 885276-64-2; tert-Butyl N-[1-(2-carboxymethylpyridin-4-yl)pyrrolidin-3-yl]carbamate
EINECS	Contact for details

Quality Control

Our (3-Boc-Amino-Pyrrolidin-1-Yl)-Pyridin-4-Yl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.