Description

(4-Boc-Amino-Piperidin-1-Yl)-Pyridin-3-Yl-Acetic Acid CAS NO 885276-22-2 is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core protected by a tert-butyloxycarbonyl (Boc) group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting G-protein-coupled receptors (GPCRs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: The piperidine-acetic acid structure makes it relevant for constructing potential inhibitors for various enzymatic targets.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways and target validation.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and new therapeutic modalities.

Basic Information

Product Name	(4-Boc-Amino-Piperidin-1-Yl)-Pyridin-3-Yl-Acetic Acid
CAS No.	885276-22-2
Molecular Formula	C17H25N3O4
Molecular Weight	335.40 g/mol
Synonyms	1-[(3-Pyridinylacetyl)]-4-[(tert-butoxycarbonyl)amino]piperidine; 4-[(tert-Butoxycarbonyl)amino]-1-(3-pyridinylacetyl)piperidine; 1-(Pyridin-3-ylacetyl)-4-(Boc-amino)piperidine; 4-(Boc-amino)-1-(3-pyridylacetyl)piperidine; N-Boc-4-amino-1-(3-pyridylacetyl)piperidine; tert-Butyl [1-(3-pyridinylacetyl)-4-piperidinyl]carbamate; (4-{[(tert-Butoxy)carbonyl]amino}-1-piperidinyl)(3-pyridinyl)methanone acetic acid form
EINECS	Contact for details

Quality Control

Our (4-Boc-Amino-Piperidin-1-Yl)-Pyridin-3-Yl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material is suitable for use in advanced pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.