Description

(3-Boc-Amino-Azetidin-1-Yl)-Pyridin-4-Yl-Acetic Acid CAS NO 885275-96-7 is a high-value, protected azetidine derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, enabling the construction of complex molecules with potential therapeutic activity. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas targeting neurological disorders and metabolic diseases.
• Protease Inhibitor Synthesis: Used in the research and production of protease inhibitors, where the azetidine scaffold is a privileged structure.
• Peptidomimetic Chemistry: Facilitates the creation of peptidomimetics by providing a constrained, nitrogen-containing heterocycle to replace peptide bonds.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A vital starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client research programs.

Basic Information

Product Name	(3-Boc-Amino-Azetidin-1-Yl)-Pyridin-4-Yl-Acetic Acid
CAS No.	885275-96-7
Molecular Formula	C15H21N3O4
Molecular Weight	307.35 g/mol
Synonyms	1-(4-Pyridinylacetyl)-3-[(1,1-dimethylethoxy)carbonyl]amino]azetidine; 3-[(tert-Butoxycarbonyl)amino]-1-(4-pyridin-4-ylacetyl)azetidine; 1-[2-(4-Pyridinyl)acetyl]-3-[[(1,1-dimethylethoxy)carbonyl]amino]azetidine; (3-((tert-Butoxycarbonyl)amino)azetidin-1-yl)(pyridin-4-yl)methanone acetic acid derivative; Boc-Azetidine-Pyridine Acetic Acid Derivative; tert-Butyl N-[1-(4-pyridin-4-ylacetyl)azetidin-3-yl]carbamate
EINECS	Contact for details

Quality Control

Our (3-Boc-Amino-Azetidin-1-Yl)-Pyridin-4-Yl-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.