Description

2-(Chloromethyl)-6-Iodoimidazo[1,2-A]Pyridine is a high-value halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its dual functionalization, featuring both a reactive chloromethyl group and an iodine atom, which enable versatile cross-coupling and substitution chemistries. It is primarily needed by pharmaceutical and agrochemical R&D teams for constructing complex molecular architectures, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for targeting neurological disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Material Science: Serves as a building block for creating specialized organic electronic materials and ligands for catalysis.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to form new carbon-carbon bonds.
• Functionalization & Derivatization: The chloromethyl group allows for further alkylation or substitution, enabling the introduction of various functional groups.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	2-(Chloromethyl)-6-Iodoimidazo[1,2-A]Pyridine
CAS No.	885275-91-2
Molecular Formula	C8H6ClIN2
Molecular Weight	292.50 g/mol
Synonyms	6-Iodo-2-(chloromethyl)imidazo[1,2-a]pyridine; 2-(Chloromethyl)-6-iodo-imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 2-(chloromethyl)-6-iodo-; 885275-91-2; 6-Iodo-2-chloromethylimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-6-Iodoimidazo[1,2-A]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry characterization. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.