Description

2-Chloromethyl-Imidazo[1,2-A]Pyridine-6-Carbonitrile is a high-value, heterocyclic organic building block featuring a reactive chloromethyl group and a nitrile functionality. This compound matters for its critical role as a versatile synthetic intermediate in the development of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those targeting the central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Research: Serves as a building block for creating functionalized polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) developing proprietary compounds.

Basic Information

Product Name	2-Chloromethyl-Imidazo[1,2-A]Pyridine-6-Carbonitrile
CAS No.	885275-72-9
Molecular Formula	C9H6ClN3
Molecular Weight	191.62 g/mol
Synonyms	2-(Chloromethyl)imidazo[1,2-a]pyridine-6-carbonitrile; 6-Cyano-2-(chloromethyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-6-carbonitrile, 2-(chloromethyl)-; 2-Chloromethyl-6-cyanoimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloromethyl-Imidazo[1,2-A]Pyridine-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.