Description

6-Chloro-3-Iodo-Imidazo[1,2-A]Pyridine is a high-value halogenated heterocyclic building block of significant interest in modern organic synthesis. Its core structure makes it a critical intermediate for the development of novel pharmaceutical compounds and advanced materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a building block for creating organic electronic materials, such as ligands for catalysts or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Employed in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Library Synthesis for Drug Discovery: Utilized in high-throughput and combinatorial chemistry to generate diverse compound libraries for screening.

Basic Information

Product Name	6-Chloro-3-Iodo-Imidazo[1,2-A]Pyridine
CAS No.	885275-59-2
Molecular Formula	C7H4ClIN2
Molecular Weight	278.48 g/mol
Synonyms	6-Chloro-3-iodoimidazo[1,2-a]pyridine; 3-Iodo-6-chloroimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 6-chloro-3-iodo-; 6-Chloro-3-iodo-imidazo[1,2-a]pyridine; 885275-59-2 (CAS Registry Number); 6-Cl-3-I-Imidazopyridine
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-3-Iodo-Imidazo[1,2-A]Pyridine is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.