Description

8-Cyano-3-Iodo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters for its unique molecular architecture, which combines an imidazopyridine core with strategically placed cyano and iodo functional groups, enabling diverse derivatization pathways. It is primarily needed by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, as well as by academic and industrial researchers developing new materials and catalysts.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various therapeutic areas, including oncology and CNS disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for creating specialized organic ligands, dyes, and functional polymers.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex molecular architectures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Academic & Contract Research: A valuable reagent for methodology development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	8-Cyano-3-Iodo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester
CAS No.	885275-52-5
Molecular Formula	C11H6IN3O2
Molecular Weight	339.09 g/mol
Synonyms	Ethyl 8-Cyano-3-iodoimidazo[1,2-a]pyridine-2-carboxylate; 3-Iodo-8-cyanoimidazo[1,2-a]pyridine-2-carboxylic Acid Ethyl Ester; Imidazo[1,2-a]pyridine-2-carboxylic acid, 8-cyano-3-iodo-, ethyl ester; 885275-52-5; CAS 885275-52-5
EINECS	Contact for details

Quality Control

Our 8-Cyano-3-Iodo-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.