Description

4-Oxo-Piperidine-1,3-Dicarboxylic Acid 1-Benzyl Ester is a high-purity, versatile piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for pharmaceutical research and development, enabling the construction of complex molecular scaffolds with high precision. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of piperidine-based drug candidates, including potential kinase inhibitors, receptor modulators, and central nervous system (CNS) active compounds.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities and improve drug-like properties.
• Process Chemistry Development: Serves as a starting material or advanced intermediate in the scalable, GMP-compliant production of active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, and insecticides that incorporate the piperidine motif for enhanced biological activity.
• Fine Chemical Production: Acts as a precursor for specialty chemicals, catalysts, and ligands used in asymmetric synthesis and other advanced chemical transformations.

Basic Information

Product Name	4-Oxo-Piperidine-1,3-Dicarboxylic Acid 1-Benzyl Ester
CAS No.	885274-95-3
Molecular Formula	C15H17NO5
Molecular Weight	291.30 g/mol
Synonyms	1-Benzyl 4-oxopiperidine-1,3-dicarboxylate; 1-Benzyl 4-oxo-1,3-piperidinedicarboxylate; 4-Oxo-1,3-piperidinedicarboxylic acid 1-benzyl ester; 1,3-Piperidinedicarboxylic acid, 4-oxo-, 1-benzyl ester; 4-Oxo-piperidine-1,3-dicarboxylic acid benzyl ester; 1-Benzyl 4-oxopiperidine-1,3-dicarboxylic acid ester; 4-Oxo-1,3-piperidinedicarboxylic acid monobenzyl ester
EINECS	Contact for details

Quality Control

Our 4-Oxo-Piperidine-1,3-Dicarboxylic Acid 1-Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance (REACH, FDA DMF where applicable) ensures material integrity for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.