Description

4-(4-Methanesulfonyl-Phenyl)-Piperidine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct piperidine and phenylsulfone structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought after by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for neurological and psychiatric disorders.
• API Synthesis: Serves as a crucial precursor in multi-step synthetic routes for target molecules in preclinical and clinical studies.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production.
• Biochemical Tool Compound: Potential use in biochemical assays and as a reference standard in analytical method development.

Basic Information

Product Name	4-(4-Methanesulfonyl-Phenyl)-Piperidine
CAS No.	885274-65-7
Molecular Formula	C12H17NO2S
Molecular Weight	239.33 g/mol
Synonyms	4-(4-Methylsulfonylphenyl)piperidine; 4-(4-Methanesulfonylphenyl)piperidine; 4-Piperidin-4-ylphenyl methyl sulfone; 1-(4-(Methylsulfonyl)phenyl)piperidine; 4-(Piperidin-4-yl)phenyl methyl sulfone; 885274-65-7; 4-(4-Methanesulphonylphenyl)piperidine
EINECS	Contact for details

Quality Control

Our 4-(4-Methanesulfonyl-Phenyl)-Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can align with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.