Description

2-(4-Boc-Piperazinyl)-2-(3-Pyridinyl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine ring and a pyridinyl acetic acid backbone. This compound is critical for medicinal chemists as it serves as a versatile building block for constructing complex molecules with potential biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates, particularly in the areas of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for neurological and oncological targets.
• Peptidomimetic Synthesis: Used to incorporate constrained, nitrogen-rich heterocyclic structures into peptide analogs to enhance stability and binding affinity.
• Ligand and Probe Development: Serves as a precursor for creating specialized chemical probes and ligands for biochemical assays and target validation studies.
• Chemical Biology Research: Employed in the synthesis of tool compounds for studying enzyme inhibition and receptor modulation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	2-(4-Boc-Piperazinyl)-2-(3-Pyridinyl)Acetic Acid
CAS No.	885274-51-1
Molecular Formula	C16H23N3O4
Molecular Weight	321.37 g/mol
Synonyms	2-(4-Boc-Piperazin-1-yl)-2-(pyridin-3-yl)acetic acid; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-2-(pyridin-3-yl)acetic acid; 2-(3-Pyridyl)-2-[4-(tert-butoxycarbonyl)-1-piperazinyl]acetic acid; 2-(4-Boc-1-piperazinyl)-2-(3-pyridinyl)acetic acid; 2-(N-Boc-piperazinyl)-2-(3-pyridyl)acetic acid; 885274-51-1; tert-Butyl 4-[2-(pyridin-3-yl)-2-(carboxymethyl)amino]piperidine-1-carboxylate (related structure).
EINECS	Contact for details

Quality Control

Our 2-(4-Boc-Piperazinyl)-2-(3-Pyridinyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.