Description

5-(4-Fluoro-Phenyl)-4-Pyridin-2-Yl-1H-Imidazole-2-Thiol is a high-purity, heterocyclic organic compound featuring a fused imidazole-thiol core with fluorophenyl and pyridyl substituents. This molecular architecture makes it a valuable and versatile pharmaceutical intermediate and research chemical for the development of novel active ingredients. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides, leveraging its heterocyclic structure for biological activity.
• Chemical Biology Probe: Acts as a scaffold or ligand in the design of molecular probes for studying biological processes and target identification.
• Material Science Research: Investigated as a monomer or functional component in the creation of specialized polymers or coordination complexes.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new synthetic routes involving imidazole derivatives.

Basic Information

Product Name	5-(4-Fluoro-Phenyl)-4-Pyridin-2-Yl-1H-Imidazole-2-Thiol
CAS No.	885271-83-0
Molecular Formula	C₁₄H₁₀FN₃S
Molecular Weight	271.31 g/mol
Synonyms	5-(4-Fluorophenyl)-4-(pyridin-2-yl)-1H-imidazole-2-thiol; 4-(2-Pyridyl)-5-(4-fluorophenyl)-2-mercaptoimidazole; 2-Mercapto-5-(4-fluorophenyl)-4-(2-pyridyl)imidazole; 5-(p-Fluorophenyl)-4-(2-pyridyl)-1H-imidazole-2-thiol; 885271-83-0; 4-Pyridin-2-yl-5-(4-fluorophenyl)-1H-imidazole-2-thiol
EINECS	Contact for details

Quality Control

Our production of 5-(4-Fluoro-Phenyl)-4-Pyridin-2-Yl-1H-Imidazole-2-Thiol adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and undergoes rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.