Description

tert-Butyl 3,7-Diazabicyclo[4.2.0]octane-3-carboxylate is a high-purity bicyclic amine derivative and a key protected intermediate in advanced organic synthesis. This compound is critical for pharmaceutical research and development, offering a versatile scaffold for constructing complex nitrogen-containing heterocycles. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries to streamline the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing novel heterocyclic libraries in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Process Chemistry Development: Used in the development and scale-up of robust synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) guidelines.
• Agrochemical Synthesis: An intermediate in the production of advanced crop protection agents and herbicides that require specific nitrogen-containing bicyclic structures.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, catalysts, and ligands used in asymmetric synthesis and other advanced chemical processes.

Basic Information

Product Name	tert-Butyl 3,7-Diazabicyclo[4.2.0]octane-3-carboxylate
CAS No.	885271-67-0
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	3-Boc-3,7-diazabicyclo[4.2.0]octane; tert-Butyl 3,7-diazabicyclo[4.2.0]octane-3-carboxylate; 3,7-Diazabicyclo[4.2.0]octane-3-carboxylic acid, 1,1-dimethylethyl ester; 3-N-Boc-3,7-diazabicyclo[4.2.0]octane; Bicyclo[4.2.0]octane-3-carboxylic acid derivative; 3-(tert-Butoxycarbonyl)-3,7-diazabicyclo[4.2.0]octane
EINECS	Contact for details

Quality Control

Our tert-Butyl 3,7-Diazabicyclo[4.2.0]octane-3-carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.