Description

6-Bromo-8-Methoxy-2H-Chromene-3-Carboxylic Acid Methyl Ester is a high-purity, functionalized chromene derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique bromo-methoxy substitution pattern makes it a valuable building block for constructing complex heterocyclic frameworks and fine-tuning molecular properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with enhanced activity.
• Material Science: Used in the research and development of organic electronic materials, such as OLEDs and sensors, due to its chromene core.
• Chemical Biology: Employed as a molecular probe or a scaffold for creating libraries in fragment-based drug discovery.
• Academic & Contract Research: Essential reagent for methodological studies in organic synthesis, including cross-coupling and cyclization reactions.

Basic Information

Product Name	6-Bromo-8-Methoxy-2H-Chromene-3-Carboxylic Acid Methyl Ester
CAS No.	885271-18-1
Molecular Formula	C₁₂H₁₁BrO₄
Molecular Weight	299.12 g/mol
Synonyms	Methyl 6-bromo-8-methoxy-2H-chromene-3-carboxylate; 6-Bromo-8-methoxy-2H-1-benzopyran-3-carboxylic acid methyl ester; 2H-1-Benzopyran-3-carboxylic acid, 6-bromo-8-methoxy-, methyl ester; 885271-18-1; Methyl 6-bromo-8-methoxy-2H-1-benzopyran-3-carboxylate; 6-Bromo-8-methoxy-2H-chromene-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-Methoxy-2H-Chromene-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.