Description

8-Bromo-6-Chloro-2H-Chromene-3-Carboxylic Acid Ethyl Ester is a high-purity chromene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated structure, which provides specific reactivity for constructing complex heterocyclic frameworks. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its halogenated chromene core.
• Material Science: Building block for creating novel organic light-emitting diodes (OLEDs) or photochromic materials due to the chromene scaffold.
• Chemical Biology: Employed as a molecular probe or a tag in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Academic & Contract Research: Essential reagent for methodological development and novel synthetic route exploration in university and CRO laboratories.

Basic Information

Product Name	8-Bromo-6-Chloro-2H-Chromene-3-Carboxylic Acid Ethyl Ester
CAS No.	885271-07-8
Molecular Formula	C₁₂H₁₀BrClO₃
Molecular Weight	317.56 g/mol
Synonyms	Ethyl 8-Bromo-6-chloro-2H-chromene-3-carboxylate; 8-Bromo-6-chloro-2H-1-benzopyran-3-carboxylic acid ethyl ester; 2H-1-Benzopyran-3-carboxylic acid, 8-bromo-6-chloro-, ethyl ester; 885271-07-8; 6-Chloro-8-bromo-2H-chromene-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of 8-Bromo-6-Chloro-2H-Chromene-3-Carboxylic Acid Ethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.