Description

2-(Piperazin-1-yl)-1,8-naphthyridine is a high-purity, specialized heterocyclic compound featuring a naphthyridine core linked to a piperazine moiety. This molecular architecture makes it a valuable and versatile building block in advanced pharmaceutical research and fine chemical synthesis. It is primarily sought after by researchers and process chemists in the life sciences sector for the development of novel active pharmaceutical ingredients (APIs) and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Chemical Synthesis Building Block: Used in organic synthesis to construct complex molecular frameworks, leveraging its reactive sites for further functionalization via alkylation, acylation, or coupling reactions.
• Ligand in Catalysis: Serves as a potential ligand for metal catalysts in asymmetric synthesis and cross-coupling reactions due to its nitrogen-rich, chelating structure.
• Agrochemical Research: Employed in the discovery and synthesis of novel crop protection agents and pesticides.
• Material Science Research: Investigated as a component in the development of organic electronic materials, such as light-emitting diodes (OLEDs) or sensors.
• Biochemical Probe Development: Utilized in medicinal chemistry to create tool compounds for studying biological pathways and protein interactions.

Basic Information

Item	Detail
Product Name	2-(Piperazin-1-yl)-1,8-Naphthyridine
CAS No.	885270-92-8
Molecular Formula	C₁₂H₁₄N₄
Molecular Weight	214.27 g/mol
Synonyms	1,8-Naphthyridine, 2-(1-piperazinyl)-; 2-(1-Piperazinyl)-1,8-naphthyridine; 2-Piperazin-1-yl-1,8-naphthyridine; 1,8-Naphthyridine, 2-piperazinyl-; 2-(Piperazin-1-yl)-1,8-naphthyridine; 2-(Piperazin-1-yl)[1,8]naphthyridine; 2-(Piperazin-1-yl)-1,8-naphthyridine; 885270-92-8
EINECS	Contact for details

Quality Control

Every batch of 2-(Piperazin-1-yl)-1,8-naphthyridine is manufactured under strict quality management protocols. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after each use to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.