Description

7-Chloro-2-(4-(Trifluoromethyl)Phenyl)Pyrazolo[1,5-A]Pyridine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system and oncological diseases. It is primarily needed by research institutions, contract research/manufacturing organizations (CROs/CMOs), and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Development: Used in the synthesis of novel compounds for crop protection and pesticide research.
• Material Science: Potential precursor for the development of organic electronic materials and functional dyes.
• Contract Synthesis: Supplied to CROs and CDMOs for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for heterocyclic chemistry studies and novel reaction methodology development.

Basic Information

Product Name	7-Chloro-2-(4-(Trifluoromethyl)Phenyl)Pyrazolo[1,5-A]Pyridine
CAS No.	885270-43-9
Molecular Formula	C14H8ClF3N2
Molecular Weight	296.67 g/mol
Synonyms	7-Chloro-2-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyridine; 2-(4-Trifluoromethylphenyl)-7-chloropyrazolo[1,5-a]pyridine; 7-Chloro-2-(4-trifluoromethylphenyl)pyrazolo[1,5-a]pyridine; Pyrazolo[1,5-a]pyridine, 7-chloro-2-[4-(trifluoromethyl)phenyl]-; 885270-43-9; 7-Chloro-2-(4-(trifluoromethyl)phenyl)-1,5-diazaindene; 7-Chloro-2-(α,α,α-trifluoro-p-tolyl)pyrazolo[1,5-a]pyridine
EINECS	Contact for details

Quality Control

Our 7-Chloro-2-(4-(Trifluoromethyl)Phenyl)Pyrazolo[1,5-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring suitability for advanced research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.