Description

(2-Oxo-3-Pyridin-4-Yl-Propyl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected amino acid derivative featuring a pyridine moiety and a tert-butyloxycarbonyl (Boc) protecting group. This compound is a critical building block in modern pharmaceutical research and development, enabling the controlled synthesis of complex peptide-like molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the creation of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug molecules, particularly those targeting neurological and inflammatory pathways.
• Peptidomimetic Research: Serves as a crucial building block for constructing peptidomimetics and constrained peptides, where the pyridine ring can act as a bioisostere or influence conformation.
• API Development: Used in process chemistry for the scale-up and optimization of routes to potential active pharmaceutical ingredients.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or molecular probes for studying biological mechanisms and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	(2-Oxo-3-Pyridin-4-Yl-Propyl)-Carbamic Acid tert-Butyl Ester
CAS No.	885269-81-8
Molecular Formula	C13H18N2O3
Molecular Weight	250.30 g/mol
Synonyms	tert-Butyl N-(2-oxo-3-(pyridin-4-yl)propyl)carbamate; Boc-3-(4-Pyridyl)-L-alanine; 4-Pyridinepropanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-, (αS)-; (S)-2-((tert-Butoxycarbonyl)amino)-3-(pyridin-4-yl)propanoic acid (cyclic tautomer); N-Boc-3-(4-pyridyl)alanine; Boc-3-(4-Pyridyl)alanine; 885269-81-8; (S)-2-(tert-Butoxycarbonylamino)-3-(4-pyridyl)propionic acid lactam form
EINECS	Contact for details

Quality Control

Our (2-Oxo-3-Pyridin-4-Yl-Propyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.