Description

8'-Methoxy-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] is a sophisticated spirocyclic organic compound featuring a fused isoquinoline and cyclopropane structure, serving as a valuable synthetic intermediate. Its unique molecular architecture makes it a critical building block for pharmaceutical research and the development of novel active ingredients. This high-purity compound is primarily utilized by research institutions and chemical manufacturers engaged in advanced organic synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, or other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct more elaborate heterocyclic systems and spirocyclic compounds.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Material Science Precursor: Investigated for the synthesis of specialized organic materials and ligands for catalytic systems.

Basic Information

Product Name	8'-Methoxy-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]
CAS No.	885269-39-6
Molecular Formula	C₁₃H₁₅NO
Molecular Weight	201.27 g/mol
Synonyms	1'H-Spiro[cyclopropane-1,4'-isoquinoline], 8'-methoxy-2',3'-dihydro-; 8'-Methoxy-1,2,3,4-tetrahydrospiro[cyclopropane-1,4'-isoquinoline]; Spiro[cyclopropane-1,4'(1'H)-isoquinoline], 8'-methoxy-2',3'-dihydro-; 8-Methoxyspiro[cyclopropane-1,4-isoquinoline]; 885269-39-6
EINECS	Contact for details

Quality Control

Our 8'-Methoxy-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.